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Cat. No.: HY-170507

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CDK-IN-16

CDK-IN-16 (Compound 5g) is a CDK2/cyclin A2 inhibitor with an IC₅₀ of 1.67 μM. CDK-IN-16 exhibits anticancer activity. The IC₅₀ of CDK-IN-16 against the AGS cell line is 3.5 μM.

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CAS No.: 3103862-82-1
Formule: C₂₃H₁₇N₃O
Masse moléculaire:351.40

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (280 KB)

CDK-IN-16 Chemical Structure

CAS No.: 3103862-82-1

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Description

CDK-IN-16 (Compound 5g) is a CDK2/cyclin A2 inhibitor with an IC₅₀ of 1.67 μM. CDK-IN-16 exhibits anticancer activity. The IC₅₀ of CDK-IN-16 against the AGS cell line is 3.5 μM^[1].

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Chemical Information

CAS No. 3103862-82-1
Masse moléculaire 351.40
Formule C₂₃H₁₇N₃O
SMILES

OC1=CC=C(C2=C3CCC4=CC=CC=C4C3=NC(C5=CC=CN=C5)=N2)C=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (280 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Saravanakumar N, et al. Novel Fused Pyrimidines as Potent Cyclin-Dependent Kinases Inhibitor for Gastric Adenocarcinoma: Combined In Vitro, In Silico Anticancer Studies. Chem Biol Drug Des. 2024 Nov;104(5):e70013. [Content Brief]

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1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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CDK-IN-16

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Chemical Information

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Références

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