TARS1 - threonyl-tRNA synthetase 1 Gene

Also Known as TARS; TTD7; ThrRS

Species: Homo sapiens (human)

Gene Type: protein coding
Gene ID: 6897

Summary

Aminoacyl-tRNA synthetases catalyze the aminoacylation of tRNA by their cognate amino acid. Because of their central role in linking Amino acids with nucleotide triplets contained in tRNAs, aminoacyl-tRNA synthetases are thought to be among the first proteins that appeared in evolution. Threonyl-tRNA synthetase belongs to the class-II Aminoacyl-tRNA Synthetase family [provided by RefSeq, Jul 2008]

TARS1 Products (1)

mRNA Protein Name
NR_047677.2

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence Références Source
enables ATP binding IMP
IMP: Inferred from mutant phenotype
25824639 GOA
enables identical protein binding IPI
IPI: Inferred from physical interaction
25824639 GOA
enables protein binding IPI
IPI: Inferred from physical interaction
25416956 GOA
enables threonine-tRNA ligase activity IDA
IDA: Inferred from direct assay
25824639 GOA
enables zinc ion binding IDA
IDA: Inferred from direct assay
25824639 GOA
Biological Process GO Annotation Evidence Références Source
involved in threonyl-tRNA aminoacylation IDA
IDA: Inferred from direct assay
25824639 GOA
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

threonine--tRNA ligase 1, cytoplasmic

  • threonine tRNA ligase 1, cytoplasmic

  • threonine--tRNA ligase, cytoplasmic

  • threonyl-tRNA synthetase, cytoplasmic

TARS1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method Références
Intra
TARS1 P26639 SULT1B1 Homo sapiens O43704
Validated Y2H
32814053
Intra
TARS1 P26639 SULT1B1 Homo sapiens O43704
Y2H Array
32814053
Intra
TARS1 P26639 SULT1B1 Homo sapiens O43704
Y2H Pooling
32814053
Intra
TARS1 P26639 TARS3 Homo sapiens A2RTX5
Y2H Prey Pooling
25416956
Intra
TARS1 P26639 TARS3 Homo sapiens A2RTX5
Y2H Prey Pooling
32296183
Intra
TARS1 P26639 TARS3 Homo sapiens A2RTX5
Y2H Array
25416956
Intra
TARS1 P26639 TARS3 Homo sapiens A2RTX5
Y2H Array
32296183
Intra
TARS1 P26639 C7orf25 Homo sapiens Q9BPX7
Y2H Array
25416956
Intra
TARS1 P26639 C7orf25 Homo sapiens Q9BPX7
Validated Y2H
25416956
Intra
TARS1 P26639 C7orf25 Homo sapiens Q9BPX7
Y2H Prey Pooling
25416956
Intra
TARS1 P26639 OPTN Homo sapiens Q96CV9
Validated Y2H
32814053
Intra
TARS1 P26639 OPTN Homo sapiens Q96CV9
Y2H Pooling
32814053
Intra
TARS1 P26639 OPTN Homo sapiens Q96CV9
Y2H Array
32814053
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (29)
Cat. No. Nom du produit
Effect
Pureté
Rare Diseases
HY-RS00028 AARS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS01933 CARS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS03532 DARS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07532 LARS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15739 WARS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17458 Aars1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS05279 GARS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS07071 KARS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS08153 MARS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS09036 NARS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11676 RARS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS12448 SARS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14209 TARM1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14210 TARS2 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS14211 TARS3 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS15604 VARS1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19198 Gars1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS19754 Wars1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS20900 Dars1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21061 Tarm1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21627 Lars1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22670 Nars1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23915 Aars1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS25686 Gars1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS26251 Wars1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27417 Dars1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS27578 Tarm1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28145 Lars1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS29184 Nars1 Rat Pre-designed siRNA Set A / Unkown