1. Gene
  2. TARS3 - threonyl-tRNA synthetase 3 Gene

TARS3 - threonyl-tRNA synthetase 3 Gene

Homo sapiens

Also known as TARSL2; ThrRS-L

Gene ID: 123283 | Gene type: protein coding

About TARS3

This gene has 7 transcripts (splice variants), 199 orthologues and 4 paralogues. Ubiquitous expression in brain (RPKM 4.4), heart (RPKM 3.4) and 25 other tissues.

Summary

Predicted to enable threonine-tRNA ligase activity. Predicted to be involved in threonyl-tRNA aminoacylation. Predicted to be located in cytoplasm and nucleus. [provided by Alliance of Genome Resources, Apr 2022]

TARS3 Products(1)

mRNA Protein Name
NM_152334.3 NP_689547.2 threonine--tRNA ligase 2, cytoplasmic

TARS3 Protein Structure

TGS

TGS: TGS domain (167 - 222)

tRNA_SAD

tRNA_SAD: Threonyl and Alanyl tRNA synthetase second additional domain (329 - 377)

tRNA-synt_2b

tRNA-synt_2b: tRNA synthetase class II core domain (G, H, P, S and T) (432 - 594)

HGTP_anticodon

HGTP_anticodon: Anticodon binding domain (699 - 789)

  • 0
  • 200
  • 400
  • 600
  • 802 a.a.
Protein Preferred Names Protein Names

threonine--tRNA ligase 2, cytoplasmic

probable threonine--tRNA ligase 2, cytoplasmic

Related Diseases

Diseases Alias
Antisynthetase Syndrome

As Syndrome

Anti-Jo1 Syndrome

Granulomatous Myositis
Diseases Alias
Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Waldenstroem'S Macroglobulinemia

Waldenstroem'S Macroglobulinemia

Macroglobulinemia Of Waldenstrom

Lymphoplasmacytic Lymphoma With Igm Gammopathy

Lymphoplasmacytic Lymphoma

Orthologs Information

Species Symbol Source ID
Bos taurus TARS3 VGNC VGNC:35606
Rattus norvegicus TARS3 RGD RGD:1311308
Canis familiaris TARS3 VGNC VGNC:47111
Mus musculus TARS3 MGD MGI:2444486
Macaca mulatta TARS3 VGNC VGNC:78205
Felis catus TARS3 VGNC VGNC:65957