country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-187637

Copy Link Print Information

Govitecan

Govitecan is a topoisomerase I inhibitor and also a linker-payload compound for antibody-drug conjugates (ADCs), with SN-38 as its active component. Govitecan serves as the linker-drug moiety of ADCs targeting CDH17-expressing cancer cells. Govitecan acts as the cytotoxic payload component of ADCs targeting Trop-2. Govitecan can be used in research related to colorectal cancer, gastric cancer, pancreatic cancer, liver cancer, metastatic triple-negative breast cancer, and other conditions.

Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.

CAS No.: 1918106-06-5
Formule: C₇₃H₉₉N₁₁O₂₂
Masse moléculaire:1482.63

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Govitecan Chemical Structure

CAS No.: 1918106-06-5

Stock

Quantité

Amount: USD 0.00

* Veuillez sélectionner la quantité avant d'ajouter des articles.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Voir tous les produits spécifiques à Isoform Topoisomerase :

Chemical Information

CAS No. 1918106-06-5
Masse moléculaire 1482.63
Formule C₇₃H₉₉N₁₁O₂₂
SMILES

O=C1N2C(C3C(C2)=C(C4=CC(O)=CC=C4N3)CC)=CC5=C1COC([C@@]5(CC)OC(OCC6=CC=C(C=C6)NC([C@H](CCCCN)NC(COCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCN7C=C(N=N7)CNC(C8CCC(CC8)CN9C(C=CC9=O)=O)=O)=O)=O)=O)=O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Wu Q, et al. WO 2025/061181 A1. International Application Published under the Patent Cooperation Treaty (PCT). LEPU BIOPHARMA CO., LTD. International Publication Date: 27 March 2025. International Application No.: PCT/CN2024/120196. International Filing Date: 20 September 2024.

[2]. Bardia A, et al. Sacituzumab Govitecan in Metastatic Triple-Negative Breast Cancer. The New England journal of medicine. 2021 Apr 22;384(16):1529-1541.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Obtenir un devis En stock

Other size

Obtenir un devis

Amount: USD 0.00

Activité biologique
- Description
Chemical Information
Pureté et documentation
Références

Nom du produit:
Cat. No.:
Quantité:
MCE Japan Authorized Agent:

Nom du produit:
CAS No.:
Species:
Pureté:
Quantité:

Govitecan

Voir tous les produits spécifiques à Isoform Topoisomerase

Activité biologique

Description

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Govitecan Related Classifications

HY-187637 Related Classifications

Bioz

Keywords

Your Recently Viewed Products