Iptocigistat
Iptocigistat (Iptocigistatum) is a cyclic GMP-AMP synthase (cGAS) inhibitor. Iptocigistat prevents excessive immune responses. Iptocigistat can be used to study inflammation-related autoimmune diseases.
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- CAS No.: 3047739-67-0
- Formule: C18H22N6O6S
- Masse moléculaire:450.47
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Iptocigistat (Compound 10) inhibits the activity of human guanylate-adenylate cyclase in a cell-free Kinase-Glo assay, with an IC50 ranging from ≥0.005 μM to <0.02 μM[1].
Iptocigistat inhibits the activity of human guanylate-adenylate synthase in cell-free LCMS assays, with an IC50 of ≥0.005 μM and <0.02 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 3047739-67-0
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Masse moléculaire 450.47
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Formule C18H22N6O6S
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SMILES
O=C1OC(C(NC2=NN=C(N3N=CC=C3C)S2)=O)=CC(NC(COC)COC)=C1OC
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Synonyms
Iptocigistatum
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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