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Cat. No.: HY-156986

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ITH15004

ITH15004 is a CNS-penetrated P2X7 antagonist, used for the study of neurodegenerative diseases.

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CAS No.: 2600675-12-3
Formule: C₁₃H₇Cl₃N₄O
Masse moléculaire:341.58

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

ITH15004 Chemical Structure

CAS No.: 2600675-12-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

ITH15004 is a CNS-penetrated P2X7 antagonist, used for the study of neurodegenerative diseases^[1].

Voir tous les produits spécifiques à Isoform P2X Receptor :

Chemical Information

CAS No. 2600675-12-3
Masse moléculaire 341.58
Formule C₁₃H₇Cl₃N₄O
SMILES

O=C(CN1C=NC2=C1N=CN=C2Cl)C3=CC=C(C=C3Cl)Cl
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Francesco Calzaferri, et al. Synthesis and Pharmacological Evaluation of Novel Non-nucleotide Purine Derivatives as P2X7 Antagonists for the Treatment of Neuroinflammation. J Med Chem. 2021 Feb 25;64(4):2272-2290. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Chemical Information
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ITH15004

High-Throughput Bioactive Compound Library

Voir tous les produits spécifiques à Isoform P2X Receptor

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

ITH15004 Related Classifications

HY-156986 Related Classifications