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Ivicentamab

(Synonyms: GEN-3009)
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Ivicentamab (GEN-3009) is a bispecific antibody targeting CD37 with dual epitopes. Ivicentamab carries an E430G mutation in the Fc region, which efficiently promotes IgG hexamer formation on the surface of target cells. Ivicentamab provides the parental variable regions for an H429F-engineered anti-CD37 bispecific antibody, enabling it to exert complement-dependent cytotoxicity in Daudi lymphoma cells. Ivicentamab is mainly used in lymphoma-related research.

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  • Pureté: 99.82%
  • CAS No.: 2364496-42-2
  • Masse moléculaire:144.88 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Ivicentamab
  • Experimental Validation Results for Ivicentamab
  • Ivicentamab Chemical Structure
    Ivicentamab Chemical Structure
CAS No.: 2364496-42-2
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Ivicentamab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized CD37 Protein, Human (HEK293, Fc, HY-P77886) can bind Ivicentamab. The EC50 for this effect is 7.22 ng/mL.

  • Ivicentamab Chemical Structure
    1/16
  • Ivicentamab
  • Immobilized CD37 Protein, Human (HEK293, Fc, HY-P77886) can bind Ivicentamab. The EC50 for this effect is 7.22 ng/mL.