MD-230254
MD-230254 is a reversible, competitive and selective inhibitor inhibitor of MAO-B with an IC50 value of 1.8 nM. MD-230254 can be used for the study of MAO-B-related neurodegenerative diseases including Parkinson’s disease and Alzheimer’s disease.
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- CAS No.: 147807-20-3
- Formule: C18H15N3O3
- Masse moléculaire:321.33
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
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MAO-B |
Chemical Information
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CAS No. 147807-20-3
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Masse moléculaire 321.33
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Formule C18H15N3O3
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SMILES
N#CCCN1N=C(C2=CC=C(OCC3=CC=CC=C3)C=C2)OC1=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Lebreton L, et al. Selective and potent monoamine oxidase type B inhibitors: 2-substituted 5-aryltetrazole derivatives. J Med Chem. 1995;38(24):4786-4792. [Content Brief]
[2]. Yoshimoto M, et al. Synthesis and characterization of novel radiofluorinated probes for positron emission tomography imaging of monoamine oxidase B. J Labelled Comp Radiopharm. 2019;62(9):580-587. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)