Nipradolol
Nipradolol (KT-210; K-351) is a potent blocker of alpha-1-adrenergic receptors. Nipradolol inhibits the increase of intraocular pressure (IOP) in an albino rabbit model induced by Phenylephrine (HY-B0769). Nipradolo suppresses the noradrenaline (NA)-induced muscles contraction, also exhibits vasodilator activity on the dog coronary artery.
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- CAS No.: 81486-22-8
- Formule: C15H22N2O6
- Masse moléculaire:326.34
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
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Activité biologique
Description
IC50 & Target
[2]|
α1-adrenergic receptor |
In Vitro
Nipradolol (1 μM; 10 min) inhibits K-induced contraction in dog muscles with an ID50 value of 0.8 μM[1].
Nipradolol (1 μM; 10 min) reduces the resting tone and to suppress the NA-induced contraction in proximal region[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 81486-22-8
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Masse moléculaire 326.34
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Formule C15H22N2O6
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SMILES
CC(C)NCC(O)COC1=C2C(CC(O[N+]([O-])=O)CO2)=CC=C1
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Synonyms
KT 210; K 351; Hypadil
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Nipradolol Related Classifications
HY-106523 Related Classifications
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