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Cat. No.: HY-125088

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Oleoylestrone

Oleoylestrone, an adipose tissue-derived hormonal signal, is a slimming agent that decreases food intake and maintains energy expenditure.

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CAS No.: 180003-17-2
Formule: C₃₆H₅₄O₃
Masse moléculaire:534.81

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (261 KB)

Oleoylestrone Chemical Structure

CAS No.: 180003-17-2

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
- In Vitro
- Essai clinique
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Oleoylestrone, an adipose tissue-derived hormonal signal, is a slimming agent that decreases food intake and maintains energy expenditure^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
Sf9	EC₅₀	~ 10 nM Compound: 1-oleoyl (table 1)	Agonistic activity as increased intracellular calcium level by human LPA3 receptor expressed in Sf9 cells Agonistic activity as increased intracellular calcium level by human LPA3 receptor expressed in Sf9 cells	[PMID: 15857137]

In Vitro

Oleoylestrone is an adipose tissue-derived hormonal signal that elicits the decrease of body fat stores. This is accomplished by decreasing white adipose tissue mass through apoptosis and massive loss of lipid, accompanied by a decrease in food intake and the maintenance of energy expenditure^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Essai clinique

NCT Number	Sponsor	Condition	Start Date	Phase A549
NCT01329991	Plexxikon\|		2011-05	PHASE1

Chemical Information

CAS No. 180003-17-2
Masse moléculaire 534.81
Formule C₃₆H₅₄O₃
SMILES

C[C@]12[C@]([H])([C@@]3(CCC4=C([C@]3(CC2)[H])C=CC(OC(CCCCCCC/C=C\CCCCCCCC)=O)=C4)[H])CCC1=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (261 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. del Mar Grasa M, et al. Corticosterone inhibits the lipid-mobilizing effects of oleoyl-estrone in adrenalectomized rats. Endocrinology. 2007 Aug;148(8):4056-63. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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