SR-32685
SR-32685 is a NAMPT activator and neuroprotective agent. SR-32685 enhances the enzymatic activity of hNAMPT, prevents intracellular NAD depletion, and protects neurons from death induced by toxic misfolded prion proteins. SR-32685 can be used in the research of protein misfolding neurodegenerative diseases and metabolic diseases.
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- CAS No.: 2791469-14-0
- Formule: C22H24N6O2S
- Masse moléculaire:436.53
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
SR-32685 protects neuronal cells against TPrP-induced death with an EC50 of 40 nM[1].
SR-32685 (1 μM) increases the activity of h-NAMPT by at least 10% at a concentration of 1 μM[1].
SR-32685 exhibits a stability of more than 15 min in h-microsome (liver)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2791469-14-0
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Masse moléculaire 436.53
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Formule C22H24N6O2S
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SMILES
O=C(C(C=NN12)=C2NC(C3=CC=C(OCC)C=C3)=CC1=S)NCCCN4C=CN=C4C
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SR-32685 Related Classifications
HY-184247 Related Classifications
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