Sulfamethazine-d4
Based on 1 Customer Validation
Sulfamethazine-d4 (Sulfadimidine-d4) is a deuterium labeled Sulfamethazine (Sulfadimidine). Sulfamethazine (Sulfadimidine) is a brain-penetrant sulfonamide antibiotic. Sulfamethazine inhibits bacterial growth by blocking the synthesis of folic acid. Sulfamethazine can be used for research on bacterial infections.
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- Pureté : 99.91%
- CAS No.: 1020719-82-7
- Formule: C12H10D4N4O2S
- Masse moléculaire:282.35
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Stockage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Activité biologique
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 1020719-82-7
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Unlabeled CAS 57-68-1
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Appearance Solid
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Masse moléculaire 282.35
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Formule C12H10D4N4O2S
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Color White to off-white
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SMILES
O=S(C1=C([2H])C([2H])=C(N)C([2H])=C1[2H])(NC2=NC(C)=CC(C)=N2)=O
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Synonyms
Sulfadimidine-d4; Sulfadimerazine-d4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
In Vitro:
DMSO : 100 mg/mL (354.17 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (283 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5417 mL | 17.7085 mL | 35.4170 mL | 88.5426 mL |
| 5 mM | 0.7083 mL | 3.5417 mL | 7.0834 mL | 17.7085 mL | |
| 10 mM | 0.3542 mL | 1.7709 mL | 3.5417 mL | 8.8543 mL | |
| 15 mM | 0.2361 mL | 1.1806 mL | 2.3611 mL | 5.9028 mL | |
| 20 mM | 0.1771 mL | 0.8854 mL | 1.7709 mL | 4.4271 mL | |
| 25 mM | 0.1417 mL | 0.7083 mL | 1.4167 mL | 3.5417 mL | |
| 30 mM | 0.1181 mL | 0.5903 mL | 1.1806 mL | 2.9514 mL | |
| 40 mM | 0.0885 mL | 0.4427 mL | 0.8854 mL | 2.2136 mL | |
| 50 mM | 0.0708 mL | 0.3542 mL | 0.7083 mL | 1.7709 mL | |
| 60 mM | 0.0590 mL | 0.2951 mL | 0.5903 mL | 1.4757 mL | |
| 80 mM | 0.0443 mL | 0.2214 mL | 0.4427 mL | 1.1068 mL | |
| 100 mM | 0.0354 mL | 0.1771 mL | 0.3542 mL | 0.8854 mL |
Keywords
- Sulfamethazine-d4
- 1020719-82-7
- Sulfadimidine-d4
- Sulfadimerazine-d4
- Isotope-Labeled Compounds
- Bacterial
- Antibiotic
- thyroid follicular hyperplasia
- Ames test
- thyroid follicular hypertrophy
- chromosomal aberration test
- thyroid peroxidase
- unscheduled DNA synthesis test
- rodent tumor
- thyroid cancer cell
- thyroxine
- pituitary thyroid-stimulating hormone
- Inhibitor
- inhibitor
- inhibit