Tapcin
Tapcin is a dual inhibitor for topoisomerase I and topoisomerase II, with IC50 of 203 and 71 nM. Tapcin inhibits proliferations of cancer cells A-375, HeLa, Huh7.5, U2-OS, A549, Caco-2 and HT29, with IC50s of 441, 1.04, 40.5, 0.002, 0.006, 0.287 and 0.842 nM, respectively. Tapcin exhibits antitumor activity in HT29 xenograft model.
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- Formule: C64H73N11O13S3
- Masse moléculaire:1300.53
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Protocole
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
Description
IC50 & Target
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Topoisomerase II 71 nM (IC50) |
Topoisomerase I 203 nM (IC50) |
Chemical Information
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Masse moléculaire 1300.53
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Formule C64H73N11O13S3
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SMILES
O=C([C@H](C)NC([C@H](C)NC(CC(O)CCCCCCCCCCC)=O)=O)NC1=CC=C(C2=NC(C3=NC(C4=NC(C(N[C@H](C(NC5=CC=C(C(NC6=C(OC(C)C)C(O)=C(C(NC7=CC=C(C(O)=O)C=C7)=O)C=C6)=O)C=C5)=O)CC(N)=O)=O)=CS4)=CS3)=CS2)C=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Tapcin Related Classifications
HY-161628 Related Classifications
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