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Cat. No.: HY-120022

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THPP-2

THPP-2 is a tetrahydropyridopyrimidine-type phosphodiesterase 10A (PDE10A) inhibitor with a K_i of 94 nM. THPP-2 is applicable to the research of schizophrenia.

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CAS No.: 1393750-01-0
Formule: C₂₇H₂₇N₇O
Masse moléculaire:465.56

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Please store the product under the recommended conditions in the Certificate of Analysis.

THPP-2 Chemical Structure

CAS No.: 1393750-01-0

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Description

THPP-2 is a tetrahydropyridopyrimidine-type phosphodiesterase 10A (PDE10A) inhibitor with a K_i of 94 nM. THPP-2 is applicable to the research of schizophrenia^[1].

IC₅₀ & Target

^[1]

PDE10A

94 nM (Ki)

Voir tous les produits spécifiques à Isoform Phosphodiesterase (PDE) :

Chemical Information

CAS No. 1393750-01-0
Masse moléculaire 465.56
Formule C₂₇H₂₇N₇O
SMILES

O=C(NC=1C=CC=CC1)N2CC=3C(=NC(=NC3CC2)C=4C=CN=CC4)N(C)CCC5=NC=CC=C5
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Raheem IT, et al. Discovery of tetrahydropyridopyrimidine phosphodiesterase 10A inhibitors for the treatment of schizophrenia. Bioorg Med Chem Lett. 2012;22(18):5903-5908. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

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Molecular Weight Molecular Weight

Calculateur de dilution

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Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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THPP-2

Voir tous les produits spécifiques à Isoform Phosphodiesterase (PDE)

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Description

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Chemical Information

Pureté et documentation

Références

Calculators

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THPP-2 Related Classifications

HY-120022 Related Classifications

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