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Cat. No.: HY-160573

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cKK-E15

cKK-E15 is a peptide-lipid that can be used to formulate LNP3 with C14PEG2000, unmodified cholesterol, and DOPE.

For research use only. We do not sell to patients.

CAS No.: 1432494-71-7
Formula: C₇₂H₁₄₄N₄O₆
Molecular Weight:1161.94

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (262 KB)

cKK-E15 Chemical Structure

CAS No.: 1432494-71-7

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

cKK-E15 is a peptide-lipid that can be used to formulate LNP3 with C14PEG2000, unmodified cholesterol, and DOPE^[1].

In Vitro

cKK-E15 is the most enriched in Kupffer cells, Endothelial cells, and hepatocytes^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1432494-71-7
Molecular Weight 1161.94
Formula C₇₂H₁₄₄N₄O₆
SMILES

O=C1NC(CCCCN(CC(CCCCCCCCCCCCC)O)CC(CCCCCCCCCCCCC)O)C(NC1CCCCN(CC(CCCCCCCCCCCCC)O)CC(CCCCCCCCCCCCC)O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (262 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Lokugamage MP, et, al. Mild Innate Immune Activation Overrides Efficient Nanoparticle-Mediated RNA Delivery. Adv Mater. 2020 Jan;32(1):e1904905. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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