CL-F-B1
CL-F-B1 is a PD-L1 PROTAC degrader, with a DC50 of 2.32 μM. CL-F-B1 promotes the ubiquitination and degradation of PD-L1. CL-F-B1 can be used in the research of colon cancer.
(Pink: PD-1/PD-L1 ligand (HY-120647); Blue: Ligands for E3 Ligase and Cereblon ligand (HY-41547); Black: linker).
For research use only. We do not sell to patients.
- Formula: C54H54N6O10
- Molecular Weight:947.04
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All PROTACs Isoforms
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Biological Activity
Chemical Information
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Molecular Weight 947.04
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Formula C54H54N6O10
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SMILES
O=C1N(C(C2=C(C=CC=C21)N[C@@H]3CC[C@@H](NC([C@@H](CO)NCC4=C(C=C(C(C)=C4)OCC5=CC=CC(C6=CC=C7OCCOC7=C6)=C5C)OCC8=CC(C#N)=CC=C8)=O)CC3)=O)C9CCC(NC9=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)