- Click Chemistry
- Alkynes
Alkynes
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Alkynes (961)
- Formula: C15H19NO
- Molecular Weight: 229.32
(E,E)-2,4-Undecadien-8,10-diynoic acid isobutylamide is a natural compound found in Acmella oleracea and is a plant growth inhibitor. (E,E)-2,4-Undecadien-8,10-diynoic acid isobutylamide inhibits the growth of cress roots and shoots and barnyard grass roots.
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- Formula: C18H17NO6
- Molecular Weight: 343.33
Mal-(1R,2S,3R,4S)-himic acid-alkyne is a trifunctional click chemistry scaffold containing complementary functionalities for copper catalyzed azide-alkyne (CuAAC), thiol-Michael addition, and inverse electron demand Diels-Alder (iEDDA) click reactions.
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- Formula: C19H13NO2S2
- Molecular Weight: 351.44
Propargyl-DTM (P39) is an alkyne group molecule that can be used to modify antibodies or antibody fragments. Propargyl-DTM can be used in research on cancer, inflammatory diseases, and cardiovascular diseases.
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- Formula: C15H24N2O2
- Molecular Weight: 264.37
pacFA is a bifunctional fatty acid with both photocrosslinking and click chemistry properties. pacFA can be metabolically incorporated into phospholipids by cells, enabling in-situ capture, identification and imaging of protein-lipid interactions in live cells and living organisms via ultraviolet crosslinking and click reactions.
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- Formula: C49H54N5O9P
- Molecular Weight: 887.95
C(Bz)-2-Propargyl amidite 2-O-propargyl C(Bz)-3-phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
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- Formula: C45H52N7O9P
- Molecular Weight: 865.91
(2R,3R,4R,5R)-5-(2-Acetamido-6-oxo-3,6-dihydro-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)-4-(prop-2-yn-1-yloxy)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
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- Formula: C47H55N4O8P
- Molecular Weight: 834.94
C8-Alkyne-dT-CE phosphoramidite is a phosphoramidite that can be used in the synthesis of oligonucleotides.
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- Formula: C20H22N4O4
- Molecular Weight: 382.41
Lenalidomide-CO-C3-NH-alkynes is an E3 ligase ligand-linker conjugate comprising Lenalidomide (HY-A0003) and a linker. Acepromazine-1-piperazinepropanamine dihydrochloride can be conjugated to a target protein ligand to form a PROTAC molecule—for instance, the PROTAC EGFR degrader 7 (HY-147858).
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- Formula: C14H14O
- Molecular Weight: 198.27
2-Phenyl-1-octen-7-yn-1-one is an alkyne-functionalized enone with site-selective reactivity toward the N-terminal α-amino group of peptides and proteins. 2-Phenyl-1-octen-7-yn-1-one can undergo click chemistry with azides via its alkyne moiety to enable further protein functionalization. 2-Phenyl-1-octen-7-yn-1-one modifies unprotected peptide libraries as well as proteins including insulin, lysozyme, RNaseA and BCArg.
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- Formula: C17H13ClFNO4
- Molecular Weight: 349.74
(Rac)-Clodinafop-propargyl is the racemic form of Clodinafop-propargyl (HY-136380). Clodinafop-propargyl is an arylphenoxypropionic acid herbicide that can be used to control the emergence of annual grasses.
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- Formula: C5H10N2
- Molecular Weight: 98.15
PEDA is a chemical intermediate. PEDA can participate in the CuAAC reaction to synthesize ethylenediamine analogs including Biot-EDA, Cy3-EDA, EDA-AG and EDA-m7Gp3G, which are used for RNA modification.
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- Formula: C20H22O2
- Molecular Weight: 294.39
Ethinylestradiol impurity 1 (9,11-Dehydro ethynyl estradiol) is an impurity of Ethinylestradiol.
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- Formula: C20H22O3
- Molecular Weight: 310.39
Ethinylestradiol impurity 2 (16-Oxo ethynyl estradiol) is an impurity of Ethinylestradiol.
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- Formula: C13H9NO2S2
- Molecular Weight: 275.35
RD0448 is a potent inhibitor of DYRK1A, DYRK1B, and DYRK2. RD0448 selectively targets the non-native (folded intermediate) state of DYRK1A and DYRK1B. The binding site of RD0448 is hidden in the native state of DYRK1A and DYRK1B, and as a stabilizing binder, it binds tightly to both DYRK1A and DYRK1B, forming a stable complex with slow dissociation kinetics. In contrast, RD0448 targets the native state of DYRK2 without selectivity between its native and non-native states, acting as a weak binder with weaker binding affinity to DYRK2 and forming a rapidly dissociating complex.
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- Formula: C13H10O3
- Molecular Weight: 214.22
Giparmen is an anti-tubercular agent. Giparmen is promising for research of fungal infections, particularly Candida.
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- Formula: C12H15N3O5
- Molecular Weight: 281.26
2'-O-Propargylcytidine is a monomeric raw material that can be used for nucleic acid synthesis.
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- Formula: C19H19N3O6
- Molecular Weight: 385.37
2'-O-Propargyl-rC(Bz) is a monomeric raw material that can be used for nucleic acid synthesis.
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- Formula: C12H14N2O6
- Molecular Weight: 282.25
2'-O-Propargyluridine is a monomeric raw material that can be used for nucleic acid synthesis.
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- Formula: C14H17N3O6
- Molecular Weight: 323.30
2'-O-Propargyl-rC(Ac) is a monomeric raw material that can be used for nucleic acid synthesis.
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