- Click Chemistry
- BCN
BCN
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BCN (85)
- Formula: C35H65ClN2O13
- Molecular Weight: 757.35
endo-BCN-PEG12-NH2 hydrochloride is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. endo-BCN-PEG12-NH2 (hydrochloride) is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- Formula: C26H30F5NO7
- Molecular Weight: 563.51
BCOT-PEF3-OPFP is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs). BCOT-PEF3-OPFP is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
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- Formula: C54H90N6O18
- Molecular Weight: 1111.32
Aminooxy-PEG2-bis-PEG3-BCN is a cleavable 5 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Aminooxy-PEG2-bis-PEG3-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- Formula: C51H81N5O18
- Molecular Weight: 1052.21
Acid-PEG1-bis-PEG3-BCN is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Acid-PEG1-bis-PEG3-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- Formula: C28H41N5O6
- Molecular Weight: 543.66
BCN-PEG4-HyNic is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). BCN-PEG4-HyNic is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- Formula: C26H37NO8S
- Molecular Weight: 523.64
BCN-PEG4-Ts is a non-cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). BCN-PEG4-Ts is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- Formula: C21H35N3O7
- Molecular Weight: 441.52
BCN-PEG3-oxyamine is a non-cleavable 3 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). BCN-PEG3-oxyamine is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- Formula: C31H39N3O7
- Molecular Weight: 565.66
APN-PEG4-BCN is a cleavable 4 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). APN-PEG4-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- Formula: C22H33NO6
- Molecular Weight: 407.50
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- Formula: C28H47N3O8
- Molecular Weight: 553.69
Boc-gly-PEG3-endo-BCN is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs. Boc-gly-PEG3-endo-BCN is also a cleavable 2 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs). Boc-gly-PEG3-endo-BCN is a click chemistry reagent, it contains a BCN group that can undergo strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing Azide groups.
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- Formula: C30H51NO10
- Molecular Weight: 585.73
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- Formula: C23H39N3O6
- Molecular Weight: 453.57
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- Formula: C30H51NO12
- Molecular Weight: 617.73
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- Formula: C38H67NO16
- Molecular Weight: 793.94
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- Formula: C24H26F5NO6
- Molecular Weight: 519.46
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- Formula: C24H40N2O7
- Molecular Weight: 468.58
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- Formula: C26H43NO8
- Molecular Weight: 497.62
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- Formula: C28H48N3O7P
- Molecular Weight: 569.67
endo-BCN-PEG3 Phosphoramidite is a nucleic acid phosphoramidite modifier containing an endo-bicyclononyne (BCN) group and a PEG3 spacer, enabling site-specific incorporation of endo-BCN-PEG3 into DNA or RNA during solid-phase oligonucleotide synthesis. endo-BCN-PEG3 Phosphoramidite introduces a BCN group that can undergo copper-free strain-promoted azide-alkyne cycloaddition (SPAAC) with azide-containing molecules or inverse electron demand Diels-Alder (IEDDA) reactions with tetrazines, enabling post-synthetic oligonucleotide labeling and bioconjugation.
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- Formula: C57H83ClN4O10
- Molecular Weight: 1019.74
Cy3-PEG7-endo-BCN is a dye derivative of Cyanine 3 (Cy3) (HY-D0822) containing 7 PEG units. Cy3-PEG7-endo-BCN contains the lyophilic bidentate macrocyclic ligand BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
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- Formula: C32H36N2O6
- Molecular Weight: 544.64
Endo-BCN-Fmoc-L-Lysine is a linker containing the lyophilic bidentate macrocyclic ligand endo-BCN, which can further synthesize macrocyclic complexes. In click chemistry, endo-BCN can react with molecules containing azide groups to form stable triazoles in the absence of catalysts.
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