1. Cytokines
  2. Recombinant Human Bone Morphogenetic Protein 7

Recombinant Human Bone Morphogenetic Protein 7

Cat. No.: HY-P7008
Handling Instructions

Recombinant Human Bone Morphogenetic Protein 7 is a member of the BMP-family, and a part of the transforming growth factor (TGF-β) superfamily, used for revision posterolateral lumbar spine fusion and for the treatment of long bone nonunion fractures after successful clinical trials.

For research use only. We do not sell to patients.

Cytokines-MedChemExpress
Size Price Stock Quantity
10 μg $190 In-stock
Estimated Time of Arrival: December 31
50 μg $690 In-stock
Estimated Time of Arrival: December 31
100 μg   Get quote  
250 μg   Get quote  

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  • Technical Parameters

  • Properties

  • Description

Synonyms
rHuBMP-7; OP-1
Species

Human

Source

E. coli

Accession

P18075

Gene ID

655

Molecular Weight

Approximately 15.7 kDa

AA Sequence

STGSKQRSQN RSKTPKNQEA LRMANVAENS SSDQRQACKK HELYVSFRDL GWQDWIIAPE GYAAYYCEGE CAFPLNSYMN ATNHAIVQTL VHFINPETVP KPCCAPTQLN AISVLYFDDS SNVILKKYRN MVVRACGCH

Biological Activity
Data is not available.
Appearance

Lyophilized powder.

Formulation

Lyophilized after extensive dialysis against solution in 30% acetonitrile, 0.1% TFA.

Endotoxin Level

<0.2 EU/μg, determined by LAL method.

Reconsititution

Reconstitute the lyophilized recombinant Human Bone Morphogenetic Protein 7 (rHuBMP-7) to 0.1-1.0 mg/mL using 10mM HAc.

Storage & Stability

Lyophilized recombinant Human Bone Morphogenetic Protein 7 (rHuBMP-7) is stored at -20°C. After reconstitution, it is stable at 4°C for 1 week or -20°C for longer. It is recommended to freeze aliquots at -20°C or -80°C for extended storage.

Shipping

Room temperature in continental US; may vary elsewhere.

Background

Bone morphogenetic protein-7 (BMP-7) is a homodimeric glycoprotein that belongs to the transforming growth factor beta (TGFβ) superfamily, functions in osteogenesis and chondrogenesis, and is involved in various cellular processes such as kidney and eye development, brown adipogenesis, and bone metastasis. Recombinant Human Bone Morphogenetic Protein 7 produced in Chinese hamster ovary (CHO) cells is approved for revision posterolateral lumbar spine fusion and for the treatment of long bone nonunion fractures after successful clinical trials[1].

Documentation
References
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Product Name:
Recombinant Human Bone Morphogenetic Protein 7
Cat. No.:
HY-P7008
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