D-Ribose(mixture of isomers)-¹³C₅

Name: D-Ribose(mixture of isomers)- 13 C 5
Brand: MedChemExpress
SKU: HY-W018772S15
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Cat. No.: HY-W018772S15 Purity: 99.90%: Data Sheet
COA

SDS
Handling Instructions
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D-Ribose(mixture of isomers)-¹³C₅ isomers)-¹³C₅ is the ¹³C labeled D-Ribose(mixture of isomers). D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner.

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D-Ribose(mixture of isomers)-<sup>13</sup>C<sub>5</sub>

D-Ribose(mixture of isomers)-¹³C₅ 화학구조

CAS No. : 202114-47-4

사이즈	재고	수량
1 mg	해외재고보유	Estimated Time of Arrival: December 31
5 mg	해외재고보유	Estimated Time of Arrival: December 31
10 mg	해외재고보유	Estimated Time of Arrival: December 31
25 mg	해외재고보유	Estimated Time of Arrival: December 31
50 mg	해외재고보유	Estimated Time of Arrival: December 31
100 mg	해외재고보유	Estimated Time of Arrival: December 31
200 mg	견적 받기
500 mg	견적 받기

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고객리뷰

Based on 1 Customer Validation

Other Forms of D-Ribose(mixture of isomers)-¹³C₅:

D-Ribose(mixture of isomers) In-stock

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Biological Activity
순도&문서
References
고객리뷰

제품 설명

D-Ribose(mixture of isomers)-¹³C₅ isomers)-¹³C₅ is the ¹³C labeled D-Ribose(mixture of isomers)^[1]. D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner^[1].

Application

1. This compound can be used as a tracer.
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

분자량

155.09

화학식

¹³C₅H₁₀O₅

CAS No.

202114-47-4

Unlabeled CAS

50-69-1

Appearance

Solid

Color

White to off-white

SMILES

O[13C@H]([13C@@H]([13CH2]O)O)[13C@H]([13CH]=O)O

선적

Room temperature in continental US; may vary elsewhere.

보관

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

용액&용해도

In Vitro:

H₂O : 100 mg/mL (644.79 mM; Need ultrasonic)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	6.4479 mL	32.2393 mL	64.4787 mL
5 mM	1.2896 mL	6.4479 mL	12.8957 mL
10 mM	0.6448 mL	3.2239 mL	6.4479 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

몰농도 계산기
농도 희석 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

Concentration _(start)

Volume _(start)

Concentration _(final)

Volume _(final)

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

순도&문서

Purity: 99.95%

Select Batch:

Data Sheet (273 KB) SDS (393 KB)

COA (248 KB) HNMR (1170 KB) CNMR (1060 KB) RP-HPLC (513 KB)

Handling Instructions (2659 KB)

References

[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]

[2]. Hong J, et al. D-ribose induces nephropathy through RAGE-dependent NF-κB inflammation. Arch Pharm Res. 2018 Aug;41(8):838-847. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	6.4479 mL	32.2393 mL	64.4787 mL	161.1967 mL
	5 mM	1.2896 mL	6.4479 mL	12.8957 mL	32.2393 mL
	10 mM	0.6448 mL	3.2239 mL	6.4479 mL	16.1197 mL
	15 mM	0.4299 mL	2.1493 mL	4.2986 mL	10.7464 mL
	20 mM	0.3224 mL	1.6120 mL	3.2239 mL	8.0598 mL
	25 mM	0.2579 mL	1.2896 mL	2.5791 mL	6.4479 mL
	30 mM	0.2149 mL	1.0746 mL	2.1493 mL	5.3732 mL
	40 mM	0.1612 mL	0.8060 mL	1.6120 mL	4.0299 mL
	50 mM	0.1290 mL	0.6448 mL	1.2896 mL	3.2239 mL
	60 mM	0.1075 mL	0.5373 mL	1.0746 mL	2.6866 mL
	80 mM	0.0806 mL	0.4030 mL	0.8060 mL	2.0150 mL
	100 mM	0.0645 mL	0.3224 mL	0.6448 mL	1.6120 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.