D-Ribose(mixture of isomers)-13C5
Based on 1 Customer Validation
D-Ribose(mixture of isomers)-13C5 isomers)-13C5 is the 13C labeled D-Ribose(mixture of isomers). D-Ribose(mixture of isomers) is an energy enhancer, and acts as a sugar moiety of ATP, and widely used as a metabolic therapy supplement for chronic fatigue syndrome or cardiac energy metabolism. D-Ribose(mixture of isomers) is active in protein glycation, induces NF-κB inflammation in a RAGE-dependent manner.
For research use only. We do not sell to patients.
- Purity : 99.90%
- CAS No.: 202114-47-4
- Formula: 13C5H10O5
- Molecular Weight:155.09
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Description
In Vitro
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS No. 202114-47-4
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Unlabeled CAS 50-69-1
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Appearance Solid
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Molecular Weight 155.09
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Formula 13C5H10O5
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Color White to off-white
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SMILES
O[13C@H]([13C@@H]([13CH2]O)O)[13C@H]([13CH]=O)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
H2O : 100 mg/mL (644.79 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53(2):211-216. [Content Brief]
[2]. Hong J, et al. D-ribose induces nephropathy through RAGE-dependent NF-κB inflammation. Arch Pharm Res. 2018 Aug;41(8):838-847. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 6.4479 mL | 32.2393 mL | 64.4787 mL | 161.1967 mL |
| 5 mM | 1.2896 mL | 6.4479 mL | 12.8957 mL | 32.2393 mL | |
| 10 mM | 0.6448 mL | 3.2239 mL | 6.4479 mL | 16.1197 mL | |
| 15 mM | 0.4299 mL | 2.1493 mL | 4.2986 mL | 10.7464 mL | |
| 20 mM | 0.3224 mL | 1.6120 mL | 3.2239 mL | 8.0598 mL | |
| 25 mM | 0.2579 mL | 1.2896 mL | 2.5791 mL | 6.4479 mL | |
| 30 mM | 0.2149 mL | 1.0746 mL | 2.1493 mL | 5.3732 mL | |
| 40 mM | 0.1612 mL | 0.8060 mL | 1.6120 mL | 4.0299 mL | |
| 50 mM | 0.1290 mL | 0.6448 mL | 1.2896 mL | 3.2239 mL | |
| 60 mM | 0.1075 mL | 0.5373 mL | 1.0746 mL | 2.6866 mL | |
| 80 mM | 0.0806 mL | 0.4030 mL | 0.8060 mL | 2.0150 mL | |
| 100 mM | 0.0645 mL | 0.3224 mL | 0.6448 mL | 1.6120 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
D-Ribose(mixture of isomers)-13C5 Related Classifications
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