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Art. -Nr.: HY-188077

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LSD1-IN-50

LSD1-IN-50 is a lysine-specific histone demethylase 1 (LSD1) inhibitor. LSD1-IN-50 inhibits the proliferation of Kasumi-1 leukemia cells and shows binding affinity to LSD-1. LSD1-IN-50 can be used for the study of cancer, particularly leukemia.

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CAS. Nr.: 1340824-39-6
Formel: C₂₃H₂₂N₆O
Molecular Weight:398.46

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

LSD1-IN-50 Chemical Structure

CAS. Nr.: 1340824-39-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Alle Histone Demethylase Isoform-spezifische Produkte anzeigen :

In Vitro

LSD1-IN-50 (compound L02) (25 μM) shows LSD-1 enzymatic inhibition with an inhibition rate of 40.49%^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 1340824-39-6
Molecular Weight 398.46
Formel C₂₃H₂₂N₆O
SMILES

N#CC1=CC=C(C2=NC(C3=CC(N=CN4CCN5CCCCC5)=C4C=C3)=NO2)C=C1
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Wang S, et al. Discovery of a Potent Lysine-Specific Histone Demethylase-1 (LSD-1) Inhibitor for Cancer Treatment via Machine Learning, Molecular Modeling, and In Vitro Validation. Chemistry (Weinheim an der Bergstrasse, Germany). 2025 Dec 01;31(67):e01379. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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Biologische Aktivität
- Beschreibung
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise

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LSD1-IN-50

Alle Histone Demethylase Isoform-spezifische Produkte anzeigen