NOX5-IN-1
NOX5-IN-1 (Compound 13) is a selective NADPH oxidase 5 (NOX5) inhibitor with an IC50s of 0.30 μM. NOX5-IN-1 significantly inhibits NOX5-dependent production of ROS in freestyle293 cells (EC50: 0.86 μM). NOX5-IN-1 can be used for NOXs related diseases research, such as cardiovascular, cancer and neuroinflammation.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C21H18N6OS
- Molecular Weight:402.47
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
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NOX5 0.3 μM (IC50) |
NOX1 >100 μM (IC50) |
NOX2 >100 μM (IC50) |
NOX4 >100 μM (IC50) |
DUOX1 >15 μM (IC50) |
Chemical Information
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Molecular Weight 402.47
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Formel C21H18N6OS
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SMILES
CC(C1=CC=C2N=C(OC2=C1)SC3=C4C(N(N=N4)CC5=CC=CC=C5)=NC=N3)C
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)