DQn-1
DQn-1 is a potent antifolate with activity against Mycobacterium tuberculosis (Mtb) (MIC90=0.03 µM). DQn-1 directly inhibits DHFR enzyme activity, with IC50s of 8.7 and 7.6 nM for Mtb and human DHFR enzyme, respectively.
For research use only. We do not sell to patients.
- CAS No.: 57343-54-1
- Formula: C16H14ClN5O2
- Molecular Weight:343.77
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
DQn-1 inhibits Mycobacterium tuberculosis, with MIC90s of 0.03 µM and 1 μM, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 57343-54-1
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Molecular Weight 343.77
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Formula C16H14ClN5O2
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SMILES
O=C(C1=CC=C(NCC2=CC=C3N=C(N)N=C(C3=C2Cl)N)C=C1)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DQn-1 Related Classifications
HY-154807 Related Classifications
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