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Cat. No.: HY-N21644

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Euphominoid E

Euphominoid E is an ent-rosane diterpenoid found in the stems of Euphorbia neriifolia and the aerial parts of Euphorbia milii, acting as an inhibitor of Epstein-Barr virus (EBV) DNA lytic replication. Euphominoid E blocks EBV lytic replication. Euphominoid E can be used for research on Epstein-Barr virus (EBV) lytic replication.

For research use only. We do not sell to patients.

CAS No.: 2113766-75-7
Formula: C₂₀H₃₀O₂
Molecular Weight:302.46

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Euphominoid E Chemical Structure

CAS No.: 2113766-75-7

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
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Biological Activity

Description

All Endogenous Metabolite Isoforms :

In Vitro

Euphominoid E (compound 5) (50 μM; 48 h) does not exhibit significant inhibition of EBV lytic replication in P3HR-1 cells, as it shows less than 50% inhibition at 50 μM^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Real Time qPCR^[2]

Cell Line:

P3HR-1 cells
Concentration:

50 μM
Incubation Time:

48 h
Result:

Showed less than 50% inhibition of EBV DNA lytic replication at 50 μM, classified as inactive.

Chemical Information

CAS No. 2113766-75-7
Molecular Weight 302.46
Formula C₂₀H₃₀O₂
SMILES

C[C@@]12C3=C(CC[C@]1(C[C@](C=C)(C)CC2)[H])C(C)(C)[C@H](O)CC3=O
Structure Classification
- Terpenoids
- Sesquiterpenes
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Kemboi D, et al. Euphorbia Diterpenes: An Update of Isolation, Structure, Pharmacological Activities and Structure-Activity Relationship. Molecules. 2021 Aug 20;26(16):5055.

[2]. Liu SN, et al. ent-Rosane diterpenoids from Euphorbia milii showing an Epstein–Barr virus lytic replication assay. RSC Advances. 2017;7(74):46938-46947.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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