C1q
C1q is the recognition subunit of the C1 complex and the initiator of the classical complement pathway. Its distinctive bouquet-like architecture assembles from six copies of a heterotrimer of A, B, and C chains, each ending in a collagen-like stalk and a globular head. The heads bind IgG and IgM in immune complexes, as well as apoptotic cells, C-reactive protein, and various pathogen surfaces, triggering activation of C1r and C1s. Produced mainly by macrophages and dendritic cells, C1q also aids in the clearance of immune debris. Hereditary C1q deficiency is strongly associated with systemic lupus erythematosus.
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C1q Recombinant Proteins (3)
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Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
