Deltoin
Deltoin is a Coumarine derivative. Deltoin can be isolated from Seseli resinosum. Deltoin shows inhibitory activity on NO. Deltoin causes a significant inhibition against paw oedema. Deltoin shows anti-inflammatory activity.
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- CAS No.: 19662-71-6
- Formule: C19H20O5
- Masse moléculaire:328.36
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HCT-116 | IC50 |
7.6 μM
Compound: 4
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Cytotoxicity against human HCT116 cells after 96 hrs by MTT assay
Cytotoxicity against human HCT116 cells after 96 hrs by MTT assay
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[PMID: 23746477] |
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Sprague Dawley (male and female, 200–250 g, carrageenan-induced paw oedema model)[1]
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Dosage:5 mg/kg; 10 mg/kg; 15 mg/kg
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Administration:i.p.
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Result:Induced a 71.05% inhibition of carrageenan-induced paw oedema at 10 mg/kg; Determined an ED₅₀ value of 5.08 mg/kg.
Chemical Information
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CAS No. 19662-71-6
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Masse moléculaire 328.36
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Formule C19H20O5
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SMILES
C/C=C(C(OC([C@@H]1CC2=CC(C=C3)=C(C=C2O1)OC3=O)(C)C)=O)\C
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Deltoin Related Classifications
HY-N17743 Related Classifications
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