Rcor1 - REST corepressor 1 Gene

Also Known as Rocr1; D12Wsu95e; mKIAA0071; 5730409O11; 6720480E22Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 217864

Summary

Enables chromatin binding activity and enzyme binding activity. Involved in erythrocyte differentiation; negative regulation of gene expression; and positive regulation of megakaryocyte differentiation. Predicted to be located in nucleoplasm. Predicted to be part of DNA repair complex; histone deacetylase complex; and transcription repressor complex. Is expressed in brain; early embryo; extraembryonic component; and nose. Orthologous to human RCOR1 (REST corepressor 1). [provided by Alliance of Genome Resources, Apr 2022]

Rcor1 Products (1)

mRNA Protein Name
NM_198023.3 NP_932140.2 REST corepressor 1

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables chromatin binding IDA
IDA: Inferred from direct assay
17392792 MGI
enables enzyme binding IPI
IPI: Inferred from physical interaction
24843136 MGI
enables protein binding IPI
IPI: Inferred from physical interaction
15907476 MGI
enables transcription corepressor activity IDA
IDA: Inferred from direct assay
17707228 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within erythrocyte differentiation IMP
IMP: Inferred from mutant phenotype
24652990 MGI
involved in erythrocyte differentiation IMP
IMP: Inferred from mutant phenotype
17707228 MGI
involved in negative regulation of gene expression IDA
IDA: Inferred from direct assay
15907476 MGI
involved in positive regulation of megakaryocyte differentiation IMP
IMP: Inferred from mutant phenotype
17707228 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

REST corepressor 1

Rcor1 Protein-protein interaction Information

Type
Protein Name Protein ID Interactor Interactor Species Interactor ID Detection Method References
Intra
Rcor1 Q8CFE3 Kdm1a Mus musculus Q6ZQ88
Anti Bait CoIP
22297846
Intra
Rcor1 Q8CFE3 Nr4a2 Mus musculus Q06219
Anti Bait CoIP
19345186
Intra
Rcor1 Q8CFE3 Nr4a2 Mus musculus Q06219
Pull Down
19345186
Intra
Rcor1 Q8CFE3 Nr4a2 Mus musculus Q06219
Anti Tag CoIP
19345186
Cross: Cross-species interaction Intra: Intraspecies interaction

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (5)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-RS12362 RXRB Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS11791 RCOR1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS21729 Rcor1 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS22773 Rcor2 Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS28246 Rcor1 Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rcor1 NCBI NCBI:23186