Phenibut
Based on 1 Customer Validation
Phenibut (β-Phenyl-GABA) is a GABA-B agonist. Phenibut acts as a GABA-mimetic, primarily at GABAB receptors. Phenibut has anxiolytic and nootropic (cognition enhancing) effects.
For research use only. We do not sell to patients.
- Purity: 99.88%
- CAS No.: 1078-21-3
- Formula: C10H13NO2
- Molecular Weight:179.22
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Phenibut is a neuropsychotropic agent. Phenibut also stimulates dopamine receptors and antagonizes β-phenethylamine (PEA), a putative endogenous anxiogenic[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 1078-21-3
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Appearance Solid
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Molecular Weight 179.22
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Formula C10H13NO2
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Color White to off-white
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SMILES
O=C(O)CC(CN)C1=CC=CC=C1
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Synonyms
β-Phenyl-GABA; 4-Amino-3-phenylbutanoic acid
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
H2O : 10 mg/mL (55.80 mM; ultrasonic and warming and heat to 60°C)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Ahuja T, et al. Phenibut (β-Phenyl-γ-aminobutyric Acid) Dependence and Management of Withdrawal: EmergingNootropics of Abuse. Case Rep Psychiatry. 2018 Apr 30;2018:9864285. [Content Brief]
[2]. Lapin I. Phenibut (beta-phenyl-GABA): a tranquilizer and nootropic drug. CNS Drug Rev. 2001 Winter;7(4):471-81. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 5.5797 mL | 27.8987 mL | 55.7973 mL | 139.4934 mL |
| 5 mM | 1.1159 mL | 5.5797 mL | 11.1595 mL | 27.8987 mL | |
| 10 mM | 0.5580 mL | 2.7899 mL | 5.5797 mL | 13.9493 mL | |
| 15 mM | 0.3720 mL | 1.8599 mL | 3.7198 mL | 9.2996 mL | |
| 20 mM | 0.2790 mL | 1.3949 mL | 2.7899 mL | 6.9747 mL | |
| 25 mM | 0.2232 mL | 1.1159 mL | 2.2319 mL | 5.5797 mL | |
| 30 mM | 0.1860 mL | 0.9300 mL | 1.8599 mL | 4.6498 mL | |
| 40 mM | 0.1395 mL | 0.6975 mL | 1.3949 mL | 3.4873 mL | |
| 50 mM | 0.1116 mL | 0.5580 mL | 1.1159 mL | 2.7899 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Phenibut Related Classifications
HY-108403 Related Classifications
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