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Cat. No.: HY-185569

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DM21-L-G NHS ester

DM21-L-G NHS ester is a toxin molecule-linker conjugate that can be used for the synthesis of ADCs, such as Opugotamig olatansine (HY-185427).

For research use only. We do not sell to patients.

CAS No.: 2776103-81-0
Formula: C₆₄H₉₀ClN₉O₂₀S₂
Molecular Weight:1405.03

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

DM21-L-G NHS ester Chemical Structure

CAS No.: 2776103-81-0

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Biological Activity

Description

DM21-L-G NHS ester is a toxin molecule-linker conjugate that can be used for the synthesis of ADCs, such as Opugotamig olatansine (HY-185427)^[1].

All Drug-Linker Conjugates for ADC Isoforms :

Chemical Information

CAS No. 2776103-81-0
Molecular Weight 1405.03
Formula C₆₄H₉₀ClN₉O₂₀S₂
SMILES

C[C@]12[C@@]([C@@H]([C@]3([H])C[C@]([C@@H](/C=C/C=C(CC4=CC(N(C(C[C@@H]2OC([C@H](C)N(C)C(CCCCCSCNC([C@H](C)NC([C@@H](C)NC([C@H](C)NC(CCCSC5C(N(C(C5)=O)CCCC(ON6C(CCC6=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C)=C(C(OC)=C4)Cl)\C)OC)(NC(O3)=O)O)C)([H])O1
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Ab O. IMGN151 - A next generation folate receptor alpha targeting antibody drug conjugate active against tumors with low, medium and high receptor expression [abstract]. Cancer Res. 2020;80(16_Supplement):2890.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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