2. Antibody-drug Conjugate/ADC Related
  3. ADC Cytotoxin
  4. DMEA-PNU-159682

DMEA-PNU-159682 (molecule D12) is a ADC cytotoxin molecule including metabolites of nemorubicin (MMDX) from liver microsomes and a potent ADCs cytotoxin PNU-159682.

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DMEA-PNU-159682 Chemical Structure

DMEA-PNU-159682 Chemical Structure

CAS No. : 1799421-48-9

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Other Forms of DMEA-PNU-159682:

DMEA-PNU-159682 Related Antibodies

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Description

DMEA-PNU-159682 (molecule D12) is a ADC cytotoxin molecule including metabolites of nemorubicin (MMDX) from liver microsomes and a potent ADCs cytotoxin PNU-159682[1][2].

IC50 & Target[1]

Daunorubicins/Doxorubicins

 

Molecular Weight

755.76

Formula

C37H45N3O14
CAS No.
SMILES

C[C@H]1[C@]2([H])[C@](N3[C@]([C@H](OCC3)OC)([H])O2)([H])C[C@](O1)([H])O[C@@H]4C5=C(C[C@](C(COC(N(C)CCNC)=O)=O)(O)C4)C(O)=C6C(C(C7=C(OC)C=CC=C7C6=O)=O)=C5O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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DMEA-PNU-159682 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

DMEA-PNU-1596821799421-48-9ADC CytotoxinADC PayloadInhibitorinhibitorinhibit

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