EGFR/HER2/TS-IN-2
EGFR/HER2/TS-IN-2 (compound 17) is a potent EGFR/HER2 and TS (Thymidylate synthase) inhibitor, with IC50 values of 0.173, 0.125, and 1.12 μM, respectively. EGFR/HER2/TS-IN-2 shows cytotoxic activity against MDA-MB-231 cancer cell lines, with an IC50 of 1.69 µM.
For research use only. We do not sell to patients.
- CAS No.: 2444364-04-7
- Formula: C26H21N7OS2
- Molecular Weight:511.62
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All EGFR Isoforms
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Biological Activity
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HER2 0.125 ± 0. μM (IC50) |
EGFR 0.173 ± 0. μM (IC50) |
Chemical Information
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CAS No. 2444364-04-7
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Molecular Weight 511.62
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Formula C26H21N7OS2
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SMILES
N#CC1=C(N2N=C(C)C=C2C)N=C(SCC(NC3=NC4=C(S3)C=C(C)C=C4)=O)N=C1C5=CC=CC=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)