Enzalutamide (Standard)
Based on 1 Customer Validation
Enzalutamide (Standard) is the analytical standard of Enzalutamide. This product is intended for research and analytical applications. Enzalutamide (MDV3100) is an androgen receptor (AR) antagonist with an IC50 of 36 nM in LNCaP prostate cells. Enzalutamide is an autophagy activator.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté : 99.98%
- CAS No.: 915087-33-1
- Formule: C21H16F4N4O2S
- Masse moléculaire:464.44
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Product Information
-
Chemical Information
- Pureté et documentation
-
Help & FAQs
-
HY-16985
DarolutamideAndrogen Receptor Antagonist -
HY-16060
ApalutamideAR Antagonist -
HY-16985R
Darolutamide (Standard)Analytical Standard -
HY-70002
EnzalutamideAndrogen Receptor Antagonist -
HY-108250
(R)-BicalutamideAndrogen Areceptor Antagonist -
HY-14249
BicalutamideAndrogen Receptor Inhibitor -
HY-B0561
SpironolactoneAldosterone/Corticoid Receptor/Androgen Antagonists -
HY-B0022
FlutamideAntiandrogen Agent -
HY-13331
ClascoteroneAndrogen Receptor Inhibitor -
HY-B0561R
Spironolactone (Standard) -
HY-100348
EPI-001Androgen Receptor Inhibitor -
HY-B0672
Estradiol valerateEstrogen Receptor/ERR Agonist
Product Information
Information
Application
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
-
CAS No. 915087-33-1
-
Appearance Solid
-
Masse moléculaire 464.44
-
Formule C21H16F4N4O2S
-
Color White to off-white
-
SMILES
S=C(N(C(C1(C)C)=O)C2=CC=C(C#N)C(C(F)(F)F)=C2)N1C3=CC(F)=C(C(NC)=O)C=C3
-
Synonyms
MDV3100 (Standard)
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Tran C, et al. Development of a second-generation antiandrogen for treatment of advanced prostate cancer. Science, 2009, 324 (5928), 787-790. [Content Brief]
[2]. Scher HI, et al. Antitumour activity of MDV3100 in castration-resistant prostate cancer: a phase 1-2 study. Lancet, 2010, 375(9724), 1437-1446. [Content Brief]
[3]. Guerrero J, et al. Enzalutamide, an androgen receptor signaling inhibitor, induces tumor regression in a mouse model of castration-resistant prostate cancer. Prostate. 2013 Sep;73(12):1291-305. [Content Brief]
[4]. Kim TH, et al. Pharmacokinetics of enzalutamide, an anti-prostate cancer drug, in rats. Arch Pharm Res. 2015 Nov;38(11):2076-82. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Enzalutamide (Standard) Related Classifications
HY-70002R Related Classifications
Powered by Bioz