D-688
D-688 is an inhibitor of Tau and Aβ. D-688 can reverse Aβ1–42-induced toxicity in SH-SH5Y cells and has significant neuroprotective properties. D-688 can improve the survival rate of Drosophila melanogaster expressing the human tau protein isoform (2N4R).
For research use only. We do not sell to patients.
- CAS No.: 2276762-07-1
- Formula: C25H28FN3O2
- Molecular Weight:421.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
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- References
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Help & FAQs
Biological Activity
Description
Chemical Information
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CAS No. 2276762-07-1
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Molecular Weight 421.51
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Formula C25H28FN3O2
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SMILES
OC1=CC=C(C=C1O)C2=CC=C(C=C2)N3CCN(CC3)CCNCC4=CC=C(C=C4)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Alzheimer’s Disease Modeling
Alzheimer’s Disease (AD) is a neurodegenerative disorder characterized by a progressive decline in cognitive functions and loss of specific types of neurons and synapses. Alzheimer's symptoms can be simulated in mice by injecting drugs (such as Aβ) or genetically modified.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
D-688 Related Classifications
HY-169197 Related Classifications
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