RXR agonist 3
RXR agonist 3 (Compound 35) is a potent, partial RXR agonist (EC50s: 3, 3, 8 nM for RXRα, RXRβ, RXRγ, respectively). RXR agonist 3 can be used in the research of Alzheimer's disease, multiple sclerosis, and lymphoma.
For research use only. We do not sell to patients.
- Formula: C19H21F3N4O2
- Molecular Weight:394.39
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
IC50 & Target
[1]|
RXR α 3 nM (EC50) |
RXRβ 3 nM (EC50) |
RXRγ 8 nM (EC50) |
Chemical Information
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Molecular Weight 394.39
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Formula C19H21F3N4O2
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SMILES
OC(CCNC1=NC(N2CCC(C)(C3=C2C=CC=C3)C)=CC(C(F)(F)F)=N1)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Alzheimer’s Disease Modeling
Alzheimer’s Disease (AD) is a neurodegenerative disorder characterized by a progressive decline in cognitive functions and loss of specific types of neurons and synapses. Alzheimer's symptoms can be simulated in mice by injecting drugs (such as Aβ) or genetically modified.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
RXR agonist 3 Related Classifications
HY-180182 Related Classifications
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