Euphorbia Factor L2
Based on 1 Customer Validation
Euphorbia factor L2, a lathyrane diterpenoid isolated from caper euphorbia seed (the seeds of Euphorbia lathyris L.), has been traditionally applied to treat cancer. Euphorbia factor L2 shows potent cytotoxicity and induces apoptosis via a mitochondrial pathway.
For research use only. We do not sell to patients.
- Purity: 99.90%
- CAS No.: 218916-51-9
- Formula: C38H42O9
- Molecular Weight:642.73
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Mass Spectrometry Natural Product Library
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Biological Activity
Chemical Information
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CAS No. 218916-51-9
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Appearance Solid
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Molecular Weight 642.73
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Formula C38H42O9
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Color White to off-white
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SMILES
O=C(/C(C)=C/[C@](C1(C)C)([H])[C@]1([H])C[C@H]2OC(C3=CC=CC=C3)=O)[C@](C[C@H](C)[C@@H]4OC(C5=CC=CC=C5)=O)(OC(C)=O)[C@@]4([H])[C@@H](OC(C)=O)C2=C
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvent & Solubility
DMSO : 83.33 mg/mL (129.65 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL. * In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Purity & Documentation
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Data Sheet (285 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.5559 mL | 7.7793 mL | 15.5586 mL | 38.8966 mL |
| 5 mM | 0.3112 mL | 1.5559 mL | 3.1117 mL | 7.7793 mL | |
| 10 mM | 0.1556 mL | 0.7779 mL | 1.5559 mL | 3.8897 mL | |
| 15 mM | 0.1037 mL | 0.5186 mL | 1.0372 mL | 2.5931 mL | |
| 20 mM | 0.0778 mL | 0.3890 mL | 0.7779 mL | 1.9448 mL | |
| 25 mM | 0.0622 mL | 0.3112 mL | 0.6223 mL | 1.5559 mL | |
| 30 mM | 0.0519 mL | 0.2593 mL | 0.5186 mL | 1.2966 mL | |
| 40 mM | 0.0389 mL | 0.1945 mL | 0.3890 mL | 0.9724 mL | |
| 50 mM | 0.0311 mL | 0.1556 mL | 0.3112 mL | 0.7779 mL | |
| 60 mM | 0.0259 mL | 0.1297 mL | 0.2593 mL | 0.6483 mL | |
| 80 mM | 0.0194 mL | 0.0972 mL | 0.1945 mL | 0.4862 mL | |
| 100 mM | 0.0156 mL | 0.0778 mL | 0.1556 mL | 0.3890 mL |
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