P7–2302
P7-2302 inhibits PDE7 and PDE4B with IC50 of 0.18 nM and 77.3 nM. P7-2302 inhibits the efflux of P-gp and BCRP (breast cancer resistance protein), exhibits low uptake in rats brain. P7-2302 can be used as a PET tracer when labeled with 18F.
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- Formule: C23H21ClF2N2O4
- Masse moléculaire:462.87
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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PDE7 0.18 nM (IC50) |
PDE4B 77.3 nM (IC50) |
Chemical Information
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Masse moléculaire 462.87
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Formule C23H21ClF2N2O4
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SMILES
O=C(N1CC(F)C1)C2=C(OC3=C4C(NC(OC45CCCCC5)=O)=C(Cl)C=C3)C(F)=CC=C2
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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