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Cat. No.: HY-153138

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FTT5 LLNs

Name: FTT5 LLNs
Brand: MedChemExpress
SKU: HY-153138
Price: 143.00 USD
Availability: InStock
Rating: 5 (1 reviews)

FTT5 LLNs are functionalized lipid-like nanoparticles for in vivo mRNA delivery and base editing.

For research use only. We do not sell to patients.

CAS No.: 2803606-43-9
Formula: C₁₂₀H₂₂₂N₆O₁₅
Molecular Weight:1989.08

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

FTT5 LLNs Chemical Structure

CAS No.: 2803606-43-9

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

FTT5 LLNs are functionalized lipid-like nanoparticles for in vivo mRNA delivery and base editing^[1].

Chemical Information

CAS No. 2803606-43-9
Molecular Weight 1989.08
Formula C₁₂₀H₂₂₂N₆O₁₅
SMILES

O=C(C1=CC(C(NCCCN(CCCCCCCCC(OC(CCCCC)CC)=O)CCCCCCCCC(OC(CCCCC)CC)=O)=O)=CC(C(NCCCN(CCCCCCCCC(OC(CCCCC)CC)=O)CCCCCCCCC(OC(CCCCC)CC)=O)=O)=C1)NCCCN(CCCCCCCCC(OC(CCCCC)CC)=O)CCCCCCCCC(OC(CCCCC)CC)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Molecular Biology

RNA extraction experimental
By lysing cells, releasing RNA, and removing impurities such as proteins and DNA, high-purity RNA products are finally obtained. The commonly used traditional method is the guanidine isothiocyanate/phenol/chloroform method (Trizol), which is suitable for a variety of animal materials including animal tissues, microorganisms, cultured cells, etc., and most plant materials.
Base editing
Base editing introduces targeted single-base substitutions without intentionally generating double-stranded DNA breaks or requiring donor DNA templates; cytosine base editors mainly mediate C•G-to-T•A changes, while adenine base editors mediate A•T-to-G•C changes. The readout is the fraction of sequencing reads carrying the intended base conversion at the target site, together with bystander edits, indels, and off-target edits when measured.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Zhang X, et al. Functionalized lipid-like nanoparticles for in vivo mRNA delivery and base editing. Sci Adv. 2020 Aug 21;6(34):eabc2315. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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