Galangal acetate
Galangal acetate is a wasabi-like spicy compound.
For research use only. We do not sell to patients.
- CAS No.: 52946-22-2
- Formula: C13H14O4
- Molecular Weight:234.25
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Biological Activity
Description
Galangal acetate is a wasabi-like spicy compound[1].
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| B16-4A5 | IC50 |
5 μM
Compound: 2
|
Antimelanogenic activity in theophylline-stimulated mouse B16-4A5 cells assessed as inhibition of melanogenesis after 72 hrs relative to control
Antimelanogenic activity in theophylline-stimulated mouse B16-4A5 cells assessed as inhibition of melanogenesis after 72 hrs relative to control
|
[PMID: 27756508] |
| HeLa | IC50 |
0.98 μM
Compound: 1, ACA
|
Inhibition of HIV1 HA-tagged Rev nuclear export expressed in human HeLa cells assessed as cellular localization after 12 hrs by FITC-labelled indirect fluorescence microscopy
Inhibition of HIV1 HA-tagged Rev nuclear export expressed in human HeLa cells assessed as cellular localization after 12 hrs by FITC-labelled indirect fluorescence microscopy
|
[PMID: 20219373] |
| HL-60 | IC50 |
2 μM
Compound: ACA
|
Cytotoxicity against human HL60 cells assessed as growth inhibition after 3 days
Cytotoxicity against human HL60 cells assessed as growth inhibition after 3 days
|
[PMID: 25801158] |
| IM-9 | IC50 |
2.1 μM
Compound: ACA
|
Cytotoxicity against human IM9 cells assessed as growth inhibition after 3 days
Cytotoxicity against human IM9 cells assessed as growth inhibition after 3 days
|
[PMID: 25801158] |
| RBL-2H3 | IC50 |
12 μM
Compound: 1
|
Antiallergic activity against antigen-IgE-mediated degranulation in rat RBL2H3 cells assessed as inhibition of DNP-BSA-induced IL4 release preincubated for 10 mins before DNP-BSA challenge measured after 4 hrs
Antiallergic activity against antigen-IgE-mediated degranulation in rat RBL2H3 cells assessed as inhibition of DNP-BSA-induced IL4 release preincubated for 10 mins before DNP-BSA challenge measured after 4 hrs
|
[PMID: 19414259] |
| RBL-2H3 | IC50 |
12 μM
Compound: 1
|
Inhibitory activity against IL-4 production in RBL-2H3 cells was determined
Inhibitory activity against IL-4 production in RBL-2H3 cells was determined
|
[PMID: 12951092] |
| RBL-2H3 | IC50 |
15 μM
Compound: 1
|
Inhibitory activity against release of beta-hexosaminidase from RBL-2H3 cells
Inhibitory activity against release of beta-hexosaminidase from RBL-2H3 cells
|
[PMID: 12951092] |
| RBL-2H3 | IC50 |
17 μM
Compound: 1
|
Antiallergic activity against antigen-IgE-mediated degranulation in rat RBL2H3 cells assessed as inhibition of DNP-BSA-induced beta-hexosaminidase release preincubated for 10 mins before DNP-BSA challenge measured after 10 mins
Antiallergic activity against antigen-IgE-mediated degranulation in rat RBL2H3 cells assessed as inhibition of DNP-BSA-induced beta-hexosaminidase release preincubated for 10 mins before DNP-BSA challenge measured after 10 mins
|
[PMID: 19414259] |
| RBL-2H3 | IC50 |
17 μM
Compound: 1
|
Antiallergic activity against antigen-IgE-mediated degranulation in rat RBL2H3 cells assessed as inhibition of DNP-BSA-induced TNFalpha release preincubated for 10 mins before DNP-BSA challenge measured after 4 hrs
Antiallergic activity against antigen-IgE-mediated degranulation in rat RBL2H3 cells assessed as inhibition of DNP-BSA-induced TNFalpha release preincubated for 10 mins before DNP-BSA challenge measured after 4 hrs
|
[PMID: 19414259] |
| RBL-2H3 | IC50 |
17 μM
Compound: 1
|
Inhibitory activity against TNF-alpha production in RBL-2H3 cells was determined
Inhibitory activity against TNF-alpha production in RBL-2H3 cells was determined
|
[PMID: 12951092] |
Chemical Information
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CAS No. 52946-22-2
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Molecular Weight 234.25
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Formula C13H14O4
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SMILES
CC(OC1=CC=C(C=C1)[C@H](C=C)OC(C)=O)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Select Batch:
Purity:
99.98%
Assay:
99.98%
ee.:
99.98%
References
Calculators
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Dilution Calculator
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Galangal acetate Related Classifications
HY-114644 Related Classifications
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