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Cat. No.: HY-188009

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GCase modulator-2

GCase modulator-2 (Compound 1) is a glucocerebrosidase (GCase) modulator. GCase modulator-2 can be used in the research of Gaucher's disease and Parkinson's disease.

For research use only. We do not sell to patients.

CAS No.: 2923245-78-5
Formula: C₂₀H₂₀F₅N₇
Molecular Weight:453.41

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

GCase modulator-2 Chemical Structure

CAS No.: 2923245-78-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
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Biological Activity

Description

GCase modulator-2 (Compound 1) is a glucocerebrosidase (GCase) modulator. GCase modulator-2 can be used in the research of Gaucher's disease and Parkinson's disease^[1].

In Vitro

Glucocerebrosidase (GCase, encoded by the GBA gene) is a lysosomal β-glucosidase responsible for the hydrolytic degradation of glucocerebroside, and its deficiency causes Gaucher's disease.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2923245-78-5
Molecular Weight 453.41
Formula C₂₀H₂₀F₅N₇
SMILES

FC(CN1N=CC2=C1N=C(N3CCC4(CC3)CN(C4)C5=NC=CC(C(F)(F)F)=C5)C=N2)F
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Kevin Hunt, et al. Small molecule modulators of glucocerebrosidase activity and uses thereof. WO2023064343A1. 2024-04-13

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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