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Cat. No.: HY-169050

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Thalidomide-piperidine

Thalidomide-piperidine is an E3 Ligase Ligand-Linker Conjugate. Thalidomide-piperidine can be used to synthesize SMART1 (HY-W998345).

For research use only. We do not sell to patients.

CAS No.: 2924858-38-6
Formula: C₁₈H₁₉N₃O₄
Molecular Weight:341.36

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

Thalidomide-piperidine Chemical Structure

CAS No.: 2924858-38-6

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Thalidomide-piperidine is an E3 Ligase Ligand-Linker Conjugate. Thalidomide-piperidine can be used to synthesize SMART1 (HY-W998345)^[1].

All E3 Ligase Ligand-Linker Conjugates Isoforms :

Chemical Information

CAS No. 2924858-38-6
Molecular Weight 341.36
Formula C₁₈H₁₉N₃O₄
SMILES

O=C(N(C(C1=CC=C2)=O)C3CCC(NC3=O)=O)C1=C2N4CCCCC4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Peng Z, et al. Targeting Smurf1 to block PDK1-Akt signaling in KRAS-mutated colorectal cancer. Nat Chem Biol. 2024 Jul 22. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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