6-Hydroxyindole (Standard)
6-Hydroxyindole (Standard) is the analytical standard of 6-Hydroxyindole (HY-W002438). This product is intended for research and analytical applications. 6-Hydroxyindole is an orally active, endogenous long-acting OATP1B1 inhibitor. 6-Hydroxyindole does not alter the cell surface expression or subcellular localization of OATP1B1. 6-Hydroxyindole protects cells against Ferroptosis. 6-Hydroxyindole possesses intrinsic radical-trapping antioxidant activity. 6-Hydroxyindole serves as a component of oxidative hair dyes. 6-Hydroxyindole can be used in research related to renal failure and neurodegenerative diseases.
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- No. CAS: 2380-86-1
- Fòrmula: C8H7NO
- Peso molecular:133.15
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Product Information
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Chemical Information
- Pureza y Documentación
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Help & FAQs
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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No. CAS 2380-86-1
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Peso molecular 133.15
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Fòrmula C8H7NO
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SMILES
OC1=CC2=C(C=C1)C=CN2
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Structure Classification
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Initial Source
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
[1]. Masuo Y, et al. 6-Hydroxyindole is an endogenous long-lasting OATP1B1 inhibitor elevated in renal failure patients. Drug Metab Pharmacokinet. 2020;35(6):555-562. [Content Brief]
[2]. Jakaria M, et al. The role of hydroxyindoles in protecting neuronal cultures from ferroptosis. Cell Death Discov. 2025;11(1):329. Published 2025 Jul 16. [Content Brief]
[3]. Burnett CL, et al. Safety assessment of 6-hydroxyindole as used in cosmetics. Int J Toxicol. 2014;33(3 Suppl):24S-35S. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
6-Hydroxyindole (Standard) Related Classifications
HY-W002438R Related Classifications
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- 6-Hydroxyindole (Standard)
- 2380-86-1
- Reference Standards
- Biochemical Assay Reagents
- Endogenous Metabolite
- OAT
- Ferroptosis
- glutathione
- HT-22 mouse hippocampal neurons
- OATP1B1
- HEK293/OATP1B1 cells
- organic anion transporting polypeptide 1B1
- blood-brain barrier
- N27 rat dopaminergic neurons
- neurodegenerative diseases
- renal failure
- ferroptosis
- Inhibitor
- inhibitor
- inhibit