SL910102
SL910102 is a nonpeptide angiotensin AT1 receptor antagonist.
Para uso exclusivo en investigación. No vendemos a pacientes.
- No. CAS: 144756-71-8
- Fòrmula: C30H30N6O
- Peso molecular:490.60
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Descripciòn
IC50 & Target
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AT1 Receptor |
In Vitro
SL910102 (SL 91.0102-90 DL) is a unlabelled nonpeptide AT1-antagonist, which is tested for its ability to compete with [125J](Sar1-Ile8)-angiotensin II for specific AT1-receptor sites in rat lung homogenate[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 144756-71-8
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Peso molecular 490.60
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Fòrmula C30H30N6O
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SMILES
O=C1N=C(CCC2=CC=CC=C2)NC(CCCC)=C1CC3=CC=C(C4=CC=CC=C4C5=NN=NN5)C=C3
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocolo
Kinase Assay[1]
For saturation as well as displacement studies, rat lung homogenate is incubated in either Hepes-buffer or blank human or rat plasma yielding 50 μg protein per well in a total assay volume of 300 μL. To ensure equilibrium conditions (see binding kinetics), the samples are maintained for 60 min at 25°C under continuous rotation. All experiments are carried out in duplicate, and the results are confirmed with n=3-5 replicates over the following days[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SL910102 Related Classifications
HY-100292 Related Classifications
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