Aerobactin
Based on 1 Customer Validation
Aerobactin is a siderophore produced by bacteria. Aerobactin exhibits the primary activity of chelating ferric ions and transporting them into bacterial cells. Aerobactin promotes bacterial growth, biofilm formation, antioxidant stress resistance, and enhances bacterial virulence and transcellular translocation ability under iron-deficient conditions. Aerobactin is used in research on bacterial infections.
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- Pureza : 97.23%
- No. CAS: 26198-65-2
- Fòrmula: C22H36N4O13
- Peso molecular:564.54
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Almacenamiento:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Protocolo
- Pureza y Documentación
- Referencias
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Help & FAQs
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Actividad biológica
Descripciòn
IC50 & Target
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Human Endogenous Metabolite |
In Vitro
Aerobactin promotes bacterial adhesion and bacterial invasion into Caco-2 human colonic epithelial cells[1].
Aerobactin does not disrupt tight junctions in polarized Caco-2 cell monolayers[1].
Aerobactin promotes biofilm formation, confers resistance to oxidative stress, and reduces intracellular ROS accumulation in Yersinia pseudotuberculosis[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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No. CAS 26198-65-2
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Appearance Solid
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Peso molecular 564.54
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Fòrmula C22H36N4O13
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Color Light yellow to brown
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SMILES
CC(N(CCCC[C@H](NC(CC(O)(CC(N[C@@H](CCCCN(C(C)=O)O)C(O)=O)=O)C(O)=O)=O)C(O)=O)O)=O
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Structure Classification
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Initial Source
Shigella spp.
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvente y solubilidad
In Vitro:
H2O : 125 mg/mL (221.42 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocolo
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Aerobic Bacterial Batch Culture on Broth/Agar
Aerobic bacterial batch culture grows a closed inoculated population in broth or on agar without continuous medium replacement; growth readouts include turbidity/OD for total suspended biomass and colony-forming units for viable cells able to form colonies on agar. OD-based growth curves reflect light scattering by cells, but OD is instrument-, pathlength-, species-, cell-size-, and density-dependent, so OD should be calibrated or interpreted alongside viable counts when quantitative cell density is required.
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Fungal Biofilm Culture
Fungal biofilm culture is an in vitro method for growing surface-attached fungal communities, most commonly Candida albicans, on abiotic substrates such as polystyrene wells, silicone elastomer, or polymethylmethacrylate; the assay models adhesion, proliferation, filamentation, extracellular-matrix-associated maturation, and dispersion. Biofilm output can be read by optical density at 600 nm for adherent biomass, XTT reduction for metabolic activity, CFU recovery for viable attached or dispersed cells, and microscopy for architecture.
Pureza y Documentación
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Ficha de datos (277 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 1.7714 mL | 8.8568 mL | 17.7135 mL | 44.2838 mL |
| 5 mM | 0.3543 mL | 1.7714 mL | 3.5427 mL | 8.8568 mL | |
| 10 mM | 0.1771 mL | 0.8857 mL | 1.7714 mL | 4.4284 mL | |
| 15 mM | 0.1181 mL | 0.5905 mL | 1.1809 mL | 2.9523 mL | |
| 20 mM | 0.0886 mL | 0.4428 mL | 0.8857 mL | 2.2142 mL | |
| 25 mM | 0.0709 mL | 0.3543 mL | 0.7085 mL | 1.7714 mL | |
| 30 mM | 0.0590 mL | 0.2952 mL | 0.5905 mL | 1.4761 mL | |
| 40 mM | 0.0443 mL | 0.2214 mL | 0.4428 mL | 1.1071 mL | |
| 50 mM | 0.0354 mL | 0.1771 mL | 0.3543 mL | 0.8857 mL | |
| 60 mM | 0.0295 mL | 0.1476 mL | 0.2952 mL | 0.7381 mL | |
| 80 mM | 0.0221 mL | 0.1107 mL | 0.2214 mL | 0.5535 mL | |
| 100 mM | 0.0177 mL | 0.0886 mL | 0.1771 mL | 0.4428 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Aerobactin Related Classifications
HY-122280 Related Classifications
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