Artanin
Artanin is a coumarin, has biological activities related to Alzheimer’s disease. Artanin exerts function including AChE inhibitory and AChE- and self-induced amyloid beta (Aβ) aggregation inhibitory activities, with IC50s of 51 μM, 98 μM, and 124 μM, respectively.
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- No. CAS: 96917-26-9
- Fòrmula: C16H18O5
- Peso molecular:290.31
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Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
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Actividad biológica
Descripciòn
IC50 & Target
[1]|
AChE 51 μM (IC50) |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
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| U-937 | CC50 |
0.535 mM
Compound: BA-5, artanin
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Cytotoxicity against human U937 cells after 48 hrs by trypan blue assay
Cytotoxicity against human U937 cells after 48 hrs by trypan blue assay
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[PMID: 19716307] |
| U-937 | IC50 |
177.3 μM
Compound: BA-5, artanin
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Growth inhibition of human U937 cells assessed as [3H]5-methyl thymidine incorporation after 48 hrs by liquid scintillation counting
Growth inhibition of human U937 cells assessed as [3H]5-methyl thymidine incorporation after 48 hrs by liquid scintillation counting
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[PMID: 19716307] |
Chemical Information
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No. CAS 96917-26-9
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Appearance Solid
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Peso molecular 290.31
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Fòrmula C16H18O5
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Color Yellow to brown
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SMILES
C/C(C)=C/COC1=C(O2)C(C=CC2=O)=C(OC)C=C1OC
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Structure Classification
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Initial Source
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Pureza y Documentación
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Ficha de datos (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Artanin Related Classifications
HY-N2898 Related Classifications
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