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Referencia número: HY-181436

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CAY10563

CAY10563 is a pH-regulated NO donor. Under acidic conditions, CAY10563 releases NO via an acid-catalyzed ring-opening mechanism, generating sulfur-centered free radicals. CAY10563 induces pH-dependent vasodilation. CAY10563 can be used in studies related to cardiovascular and cerebrovascular diseases.

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No. CAS: 940952-42-1
Fòrmula: C₉H₄F₃NO₂S
Peso molecular:247.19

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Please store the product under the recommended conditions in the Certificate of Analysis.

CAY10563 Chemical Structure

No. CAS: 940952-42-1

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Descripciòn

Ver todos los productos específicos de isoformas NO Synthase :

In Vitro

CAY10563 (Compound 3a) (20 mM) releases NO in an acid-dependent manner at pH 5.0, with an overall NO yield of approximately 27%. No NO release is detected under neutral pH conditions, and it induces the formation of sulfur-centered radicals^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

No. CAS 940952-42-1
Peso molecular 247.19
Fòrmula C₉H₄F₃NO₂S
SMILES

[O-]C1=C(C2=CC=C(C=C2)C(F)(F)F)[S+]=NO1
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Instrucciones de manejo (2659 KB)

Referencias

[1]. Lu D, et al. 4-Aryl-1,3,2-oxathiazolylium-5-olates as pH-controlled NO-donors: the next generation of S-nitrosothiols. J Am Chem Soc. 2007;129(17):5503-5514. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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CAY10563

Ver todos los productos específicos de isoformas NO Synthase

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CAY10563 Related Classifications

HY-181436 Related Classifications