CBR Agonist-2
CBR Agonist-2 is a CB1 agonist (CB1R; CB1 ligand) with an EC50 and a Ki of 960 nM and 970 nM, respectively. CBR Agonist-2 is a promising tool for investigating the involvement of hCB1R in disorders associated with the endocannabinoid system.
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- Fòrmula: C27H27FN4O
- Peso molecular:442.53
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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hCB1-R 960 nM (EC50) |
hCB1-R 970 nM (Ki) |
CBR Agonist-2 (10 nM-1 μM; 24 hours) induces ERK1/2 activation in a dose-dependent manner in CHO cells expressing Gαq16 and hCB1[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:CHO cells expressing Gαq16 and hCB
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Concentration:10 nM; 100 nM; 1000 nM
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Incubation Time:24 Hours
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Result:Increased dose-dependent phosphorylation of ERK1/2 (pERK1/2) after CB1R stimulation by CBR Agonist-2.
Chemical Information
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Peso molecular 442.53
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Fòrmula C27H27FN4O
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SMILES
O=C(C1=CN(C2=CC=CC=C12)CCCCCF)NCC3=CC=CC=C3/N=N/C4=CC=CC=C4
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
CBR Agonist-2 Related Classifications
HY-151107 Related Classifications
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