cis-Revumenib
Based on 1 Customer Validation
cis-Revumenib (cis-SNDX-5613) is an isomer of Revumenib (HY-136175). Revumenib (SNDX-5613) is a potent and specific Menin-MLL inhibitor with a binding Ki of 0.149 nM and a cell based IC50 of 10-20 nM. Revumenib can be used for the research of MLL-rearranged (MLL-r) acute leukemias, including acute lymphoblastic leukemia (ALL) and acute myeloid leukemia (AML).
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 98.92%
- Fòrmula: C32H47FN6O4S
- Peso molecular:630.82
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Almacenamiento:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
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Anti-Blood Cancer Compound Library
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Bioactive Compound Library Max
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MCE Bioactive Compound Library
HY-L001V
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Bioactive Compound Library
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High-Throughput Bioactive Compound Library
HY-L205
Actividad biológica
Chemical Information
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Appearance Solid
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Peso molecular 630.82
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Fòrmula C32H47FN6O4S
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Color White to off-white
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SMILES
O=C(N(CC)C(C)C)C1=CC(F)=CC=C1OC2=CN=CN=C2N3CC4(CCN(C[C@H]5CC[C@@H](NS(=O)(CC)=O)CC5)CC4)C3
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Synonyms
cis-SNDX-5613
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvente y solubilidad
DMSO : 100 mg/mL (158.52 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureza y Documentación
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Ficha de datos (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.5852 mL | 7.9262 mL | 15.8524 mL | 39.6310 mL |
| 5 mM | 0.3170 mL | 1.5852 mL | 3.1705 mL | 7.9262 mL | |
| 10 mM | 0.1585 mL | 0.7926 mL | 1.5852 mL | 3.9631 mL | |
| 15 mM | 0.1057 mL | 0.5284 mL | 1.0568 mL | 2.6421 mL | |
| 20 mM | 0.0793 mL | 0.3963 mL | 0.7926 mL | 1.9815 mL | |
| 25 mM | 0.0634 mL | 0.3170 mL | 0.6341 mL | 1.5852 mL | |
| 30 mM | 0.0528 mL | 0.2642 mL | 0.5284 mL | 1.3210 mL | |
| 40 mM | 0.0396 mL | 0.1982 mL | 0.3963 mL | 0.9908 mL | |
| 50 mM | 0.0317 mL | 0.1585 mL | 0.3170 mL | 0.7926 mL | |
| 60 mM | 0.0264 mL | 0.1321 mL | 0.2642 mL | 0.6605 mL | |
| 80 mM | 0.0198 mL | 0.0991 mL | 0.1982 mL | 0.4954 mL | |
| 100 mM | 0.0159 mL | 0.0793 mL | 0.1585 mL | 0.3963 mL |
cis-Revumenib Related Classifications
HY-136175B Related Classifications
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