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Referencia número: HY-107082

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Dioxolane T

Dioxolane T is a nucleoside analogue. Dioxolane T exhibits anti-HIV activity.

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No. CAS: 136982-89-3
Fòrmula: C₉H₁₂N₂O₅
Peso molecular:228.20

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Dioxolane T Chemical Structure

No. CAS: 136982-89-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica
- Descripciòn
- Cellular Effect
Chemical Information
Pureza y Documentación
Referencias
Calculators
Help & FAQs
Classifications
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Actividad biológica

Descripciòn

Dioxolane T is a nucleoside analogue. Dioxolane T exhibits anti-HIV activity^[1].

Ver todos los productos específicos de isoformas HIV :

Cellular Effect

Cell Line	Type	Value	Description	References
CCRF-CEM	EC₅₀	0.68 μM Compound: DOT	Antiviral activity against HIV1 LAI infected in CEM cells Antiviral activity against HIV1 LAI infected in CEM cells	[PMID: 19153047]
CCRF-CEM	IC₅₀	>100 μM Compound: DOT	Cytotoxicity against human CEM cells after 3 days by MTT assay Cytotoxicity against human CEM cells after 3 days by MTT assay	[PMID: 19153047]
PBMC	IC₅₀	>100 μM Compound: DOT	Cytotoxicity against human PBM cells after 3 days by MTT assay Cytotoxicity against human PBM cells after 3 days by MTT assay	[PMID: 19153047]
Vero	IC₅₀	>100 μM Compound: 11	Cytotoxicity in vero cells. Cytotoxicity in vero cells.	[PMID: 1597854]
Vero	IC₅₀	>100 μM Compound: DOT	Cytotoxicity against african green monkey Vero cells after 3 days by MTT assay Cytotoxicity against african green monkey Vero cells after 3 days by MTT assay	[PMID: 19153047]

Chemical Information

No. CAS 136982-89-3
Peso molecular 228.20
Fòrmula C₉H₁₂N₂O₅
SMILES

O=C1N(C=C(C(N1)=O)C)[C@@H]2O[C@@H](OC2)CO
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Kim HO, et al. Asymmetric synthesis of 1, 3-dioxolane-pyrimidine nucleosides and their anti-HIV activity. Journal of Medicinal Chemistry. 1992 May;35(11):1987-95. [Content Brief]

Calculators

Calculadora de molaridad

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculadora de dilución

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Actividad biológica
- Descripciòn
Chemical Information
Pureza y Documentación
Referencias

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Dioxolane T

Ver todos los productos específicos de isoformas HIV