Sele - selectin E Gene

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 25544

Summary

Predicted to enable several functions, including oligosaccharide binding activity; Phospholipase binding activity; and sialic acid binding activity. Involved in inflammatory response; leukocyte migration; and response to cytokine. Predicted to be located in several cellular components, including caveola; clathrin-coated pit; and perinuclear region of cytoplasm. Predicted to be integral component of plasma membrane. Predicted to be active in external side of plasma membrane and extracellular space. Human ortholog(s) of this gene implicated in IgA glomerulonephritis; brain ischemia; cerebrovascular disease; and coronary artery disease. Orthologous to human SELE (Selectin E). [provided by Alliance of Genome Resources, Apr 2022]

Sele Products (1)

mRNA Protein Name
NM_138879.1 NP_620234.1 E-selectin precursor

Gene Ontology

  • Biological Process
Biological Process GO Annotation Evidence Referencias Source
involved in leukocyte migration IEP
IEP: Inferred from expression pattern
7544926 RGD
involved in response to cytokine IEP
IEP: Inferred from expression pattern
19489247 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

E-selectin

  • CD62 antigen-like family member E

  • ELAM-1

  • LECAM2

  • endothelial leukocyte adhesion molecule 1

  • leukocyte-endothelial cell adhesion molecule 2

  • selectin, endothelial cell

Recombinant Sele Proteins

Referencia número Nombre del producto Accession Pureza
HY-P73043 E-Selectin/CD62E Protein, Rat (HEK293, Fc) P98105 (W22-P494) ≥ 95%, as determined by reducing SDS-PAGE.
HY-P73044 E-Selectin/CD62E Protein, Rat (HEK293, His) P98105 (W22-P494) ≥ 95%, as determined by reducing SDS-PAGE.

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Referencia número Nombre del producto
Efecto
Pureza
Rare Diseases
HY-RS12632 SELE Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS17415 Sele Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS23869 Sele Rat Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Sele NCBI NCBI:6401