GSK137
GSK137 is an orally active, potent and selective B-cell lymphoma 6 (BCL6) inhibitor. GSK137 blocks the interaction between BCL6 and corepressors (e.g., SMRT), reducing the number of germinal center B cells. GSK137 is promising for research of autoimmune diseases such as systemic lupus erythematosus (SLE) and B-cell-related tumors such as diffuse large B-cell lymphoma.
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- No. CAS: 2728727-91-9
- Fòrmula: C21H19FN6
- Peso molecular:374.41
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Chemical Information
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No. CAS 2728727-91-9
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Peso molecular 374.41
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Fòrmula C21H19FN6
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SMILES
FC1=C(N2N=C1)N[C@@H](C[C@@H]2C3=C(N=CC=C3)C)C4=CC=CC5=C4C=CC(N)=N5
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GSK137 Related Classifications
HY-148631 Related Classifications
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